L2 Daily — 2026-04-18 (CORRECTED)
Supersedes the 17:00 auto-L2 which captured pre-Cheaha-work state and falsely reported Cheaha SSH as a blocker.
Active Aims
- Aim 2 Computational analysis — Tasks 2.1, 2.2, 2.3 DONE
- Aim 3 Literature — Task 3.1 DONE (29 PubMed papers 2024–2026)
- Aim 4 Cheaha SBDD — Task 4.1 DONE, Task 4.2 active
- Aim 5 Infrastructure — liveness + notifier + resilience + AGE landed
Current Task
Task 4.2 / G-007 iter 1 stage P — scale Vina from 3 to top-20 ligands.
Today’s outputs
| Task | Artifact | Key number |
|---|---|---|
| 2.1 | figures/pchembl_dist.png | n=1011, mean 5.995 |
| 2.2 | data/aim2_top20_inhibitors.csv | rank1 CHEMBL4541133 pv=9.52 |
| 2.3 | data/aim2_pdb_binding_sites.json | 5 PDBs, 3 with ligands |
| 3.1 | data/aim3_pubmed_phgdh_allosteric.json | 29 papers 2024-2026 |
| 4.1 | Cheaha workspace + Vina dock | -6.2 kcal/mol best pose |
Blockers
None. Earlier “Cheaha SSH blocker” was false — ~/.ssh/config alias
cheaha (user=jakechen) works from W0 without VPN.
Incidents today
- RED iteration alert at 14:06 (Task 4.1 R stalled 6 h) — legitimate catch
- Root cause: PLEASER stage R had no auto-exit
- Fixed:
skills/resilience/scripts/post_r_watchdog.py— R > 10 min auto-promotes - Liveness currently 10/10 green
Next 24 h
- Task 4.2: dock all top-20 into 6RIH K4T, ranked CSV + scatter plot
- L2 cron moves from 17:00 → 23:00 so EOD report captures full day
- Wiki publish gate: drafts in
wiki_drafts/awaiting your publish button
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