Waldenström’s Macroglobulinemia

A rare B-cell lymphoma characterized by MYD88 overexpression. Mentioned at Session I.

SDDS 2026 Context

SGR-1505 (Schrödinger) — a physics-discovered compound — achieved 100% response rate in Waldenström’s macroglobulinemia, with MYD88 overexpression providing the genetic rationale. Broader lymphoma response was uneven.